Professor Siwicki organised the first fish viral diseases diagnosis laboratory in Poland where he developed new methods for diagnosis of IPN, VHS, IHN and SVC. In the Department of Fish Pathology and Immunology National Inland Fisheries Institute he used several techniques for the diagnosis of viral diseases in fish, seroneutralization test (OlE), IF, immuno-electron microscopy method (IE), ELISA, Immunoblot, ISPA and molecular methods.
Professor Siwicki has studied the effects of environmental contamination and chemotherapeutics on the non-specific defence mechanisms and specific immune response in aquatic animals and mammalian. He has written over 30 papers about in vitro and in vivo effects of heavy metals, pesticides and chemotherapeutics on the immuno-competence cells activity, cell-mediated immunity and specific immune response in fish and other animals.
Professor Siwicki has studied stimulation and modulation of cellular and humoral defence mechanisms in aquatic animals and mammalian. He recognised that the application of immunostimulants for modulating the defence mechanisms and protection of fish against diseases was increasingly important in aquaculture for improving efficiency and profitability and he proved that the use of immunostimulants for inducing protection against diseases was very important for reducing the use of antibiotics and other chemotherapeutics in aquaculture. Simultaneously, Professor Siwicki developed natural immunostimulants for modulation of non-specific defence mechanisms and specific immune response after immunosuppression induced by pollutants in human and veterinary medicine. He has written over 40 papers about in vitro and in vivo effects of immunostimulants on the cellular and humoral defence mechanisms in aquatic animals and mammalian. |